Early Detection of Cardiovascular Disease

Outcome/Accomplishment

An advanced technique for measuring biomarkers indicative of cardiovascular disease has been developed by a Texas A&M University (TAMU) doctoral student researcher in collaboration with an industry partner. This research was supported by the U.S. National Science Foundation (NSF)-funded Precise Advanced Technologies and Health Systems for Underserved Populations (NSF PATHS-UP) Engineering Research Center (ERC), headquartered at TAMU, with partners from the University of California at Los Angeles, Rice University, and Florida International University.

Impact/Benefits

This project was undertaken by Cyril Soliman, working with faculty advisor Sam Mabbott, and Wasatch Photonics, a member of the NSF PATHS-UP Industry and Practitioner Advisory Board as part of the Center’s efforts to develop Lab-in-your-Palm and Lab-on-a-Wrist technology, bringing better diagnostic tools to the point of care. The result was a multi-modal spectroscopic platform that can measure multiple signals from a single sample site. This work resulted in both an advanced prototype system, and Soliman earning his Ph.D. and publishing the results.

Explanation/Background

This spectroscopic platform is capable of measuring both fluorescence and molecular vibrations (Surface-enhanced Raman Scattering [SERS]), two characteristics that are key to identifying disease biomarkers.

Pictured on the left is a Solidworks model of the dual Raman and fluorescence spectrometer highlighting the Lab-in-your-Palm form. On the right is an image of the assembled dual spectrometer.
Credit:
NSF PATHS-UP

Location

Houston, Texas

e-mail

info@newtcenter.org

website

http://www.newtcenter.org

Start Year

Energy and Sustainability

Energy and Sustainability Icon
Energy and Sustainability Icon

Energy, Sustainability, and Infrastructure

Lead Institution

Rice University

Core Partners

Arizona State University, University of Texas at El Paso, Yale University

Fact Sheet

NEWT Fact Sheet.pdf
Pictured on the left is a Solidworks model of the dual Raman and fluorescence spectrometer highlighting the Lab-in-your-Palm form. On the right is an image of the assembled dual spectrometer.
Credit:
NSF PATHS-UP

Outcome/Accomplishment

An advanced technique for measuring biomarkers indicative of cardiovascular disease has been developed by a Texas A&M University (TAMU) doctoral student researcher in collaboration with an industry partner. This research was supported by the U.S. National Science Foundation (NSF)-funded Precise Advanced Technologies and Health Systems for Underserved Populations (NSF PATHS-UP) Engineering Research Center (ERC), headquartered at TAMU, with partners from the University of California at Los Angeles, Rice University, and Florida International University.

Location

Houston, Texas

e-mail

info@newtcenter.org

website

http://www.newtcenter.org

Start Year

Energy and Sustainability

Energy and Sustainability Icon
Energy and Sustainability Icon

Energy, Sustainability, and Infrastructure

Lead Institution

Rice University

Core Partners

Arizona State University, University of Texas at El Paso, Yale University

Fact Sheet

NEWT Fact Sheet.pdf

Impact/benefits

This project was undertaken by Cyril Soliman, working with faculty advisor Sam Mabbott, and Wasatch Photonics, a member of the NSF PATHS-UP Industry and Practitioner Advisory Board as part of the Center’s efforts to develop Lab-in-your-Palm and Lab-on-a-Wrist technology, bringing better diagnostic tools to the point of care. The result was a multi-modal spectroscopic platform that can measure multiple signals from a single sample site. This work resulted in both an advanced prototype system, and Soliman earning his Ph.D. and publishing the results.

Explanation/Background

This spectroscopic platform is capable of measuring both fluorescence and molecular vibrations (Surface-enhanced Raman Scattering [SERS]), two characteristics that are key to identifying disease biomarkers.